SEARCH

SEARCH BY CITATION

Keywords:

  • atherosclerosis;
  • lipid droplet;
  • lipodystrophy;
  • metabolic syndrome;
  • triglyceride storage

Lipid droplets (LDs) are dynamic, cytosolic lipid-storage organelles found in nearly all cell types. Too many or too few LDs during excess or deficient fat storage lead to many different human diseases. Recent insights into LD biology and LD protein functions shed new light on mechanisms underlying those metabolic pathologies. These findings will likely provide opportunities for treatment of diseases associated with too much or too little fat.