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Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

  1. Suriyan Ponnusamy1,2,
  2. Shanmugam Panneer Selvam1,2,
  3. Shikhar Mehrotra2,3,
  4. Toshihiko Kawamori2,4,8,
  5. Ashley J. Snider2,5,6,
  6. Lina M. Obeid2,5,6,
  7. Yuan Shao2,4,
  8. Roger Sabbadini7,
  9. Besim Ogretmen1,2,*

Article first published online: 18 JUN 2012

DOI: 10.1002/emmm.201200244

Issue

EMBO Molecular Medicine

EMBO Molecular Medicine

Volume 4, Issue 8, pages 761–775, August 2012

Additional Information

How to Cite

Ponnusamy, S., Selvam, S. P., Mehrotra, S., Kawamori, T., Snider, A. J., Obeid, L. M., Shao, Y., Sabbadini, R. and Ogretmen, B. (2012), Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. EMBO Mol Med, 4: 761–775. doi: 10.1002/emmm.201200244

Author Information

  1. 1

    Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA

  2. 2

    Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA

  3. 3

    Department of Surgery, Medical University of South Carolina, Charleston, SC, USA

  4. 4

    Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA

  5. 5

    Department of Medicine, Medical University of South Carolina, Charleston, SC, USA

  6. 6

    Ralph H. Johnson VA Medical Center, Charleston, SC, USA

  7. 7

    Lpath Inc., San Diego, CA, USA

  8. 8

    Present address: University of Hawaii Cancer Center, Cancer Biology Program, Honolulu, HI, USA

*Tel: +1 843 792 0940; Fax: +1 843 792 2556

Publication History

  1. Issue published online: 3 AUG 2012
  2. Article first published online: 18 JUN 2012
  3. Manuscript Accepted: 5 APR 2012
  4. Manuscript Revised: 30 MAR 2012
  5. Manuscript Received: 26 JAN 2012

Funded by

  • National Institutes of Health. Grant Numbers: CA088932, DE016572, CA097165 to BO
  • NIH. Grant Numbers: C06 RR015455, P30 CA138313

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