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Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

  1. Ilirjana Bajrami1,
  2. Asha Kigozi1,
  3. Antoinette Van Weverwijk1,
  4. Rachel Brough1,2,
  5. Jessica Frankum1,
  6. Christopher J. Lord1,*,
  7. Alan Ashworth1,2,*

Article first published online: 30 AUG 2012

DOI: 10.1002/emmm.201201250

Issue

EMBO Molecular Medicine

EMBO Molecular Medicine

Volume 4, Issue 10, pages 1087–1096, October 2012

Additional Information

How to Cite

Bajrami, I., Kigozi, A., Van Weverwijk, A., Brough, R., Frankum, J., Lord, C. J. and Ashworth, A. (2012), Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells. EMBO Mol Med, 4: 1087–1096. doi: 10.1002/emmm.201201250

Author Information

  1. 1

    The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK

  2. 2

    Cancer Research UK Gene Function Laboratory, The Institute of Cancer Research, London, UK

*Tel: +44 0207 1535334; Fax: +44 0207 3523299

Publication History

  1. Issue published online: 2 OCT 2012
  2. Article first published online: 30 AUG 2012
  3. Manuscript Accepted: 10 JUL 2012
  4. Manuscript Revised: 28 JUN 2012
  5. Manuscript Received: 1 FEB 2012

Funded by

  • Breakthrough Breast Cancer, Cancer Research UK
  • AACR as part of the Stand Up to Cancer Breast Cancer Dream Team
  • NHS
  • Funded Access

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    Antonio F. Santidrian, Akemi Matsuno-Yagi, Melissa Ritland, Byoung B. Seo, Sarah E. LeBoeuf, Laurie J. Gay, Takao Yagi, Brunhilde Felding-Habermann, Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression, Journal of Clinical Investigation, 2013, 123, 3, 1068

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    Gianluca Papeo, Elena Casale, Alessia Montagnoli, Alessandra Cirla, PARP inhibitors in cancer therapy: an update, Expert Opinion on Therapeutic Patents, 2013, 23, 4, 503

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