These authors contributed equally to this work.
MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction
Article first published online: 22 JUL 2013
Copyright © 2013 EMBO Molecular Medicine
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
EMBO Molecular Medicine
Volume 5, Issue 9, pages 1402–1414, September 2013
How to Cite
Li, J., Li, J., Liu, X., Qin, S., Guan, Y., Liu, Y., Cheng, Y., Chen, X., Li, W., Wang, S., Xiong, M., Kuzhikandathil, E. V., Ye, J.-H. and Zhang, C. (2013), MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction. EMBO Mol Med, 5: 1402–1414. doi: 10.1002/emmm.201201900
- Issue published online: 3 SEP 2013
- Article first published online: 22 JUL 2013
- Manuscript Accepted: 17 JUN 2013
- Manuscript Revised: 2 MAY 2013
- Manuscript Received: 17 AUG 2012
- NIH Grants, HL095707, R21HL109656 and R21NR013876, CZ, PI
- NIH Grant, AA016964, J. E, PI
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Figure S1. Delivery of Ad-miR-382 to the rat NAc increases the expression of miR-382 in NAc, but not in the neighbouring brain areas.
Figure S2. The successful up-regulation of miR-382 via Ad-miR-382 in NAc of rats at 7 days after drinking of alcohol.
Figure S3. The successful modulation of DRD1 and DeltaFosB via Ad-miR-382 was verified by Western blot analysis at 7 days after drinking of alcohol.
Table S1. Comparison of membrane properties of NAc MSNs in acute brain slices of rats received NAc injection of saline or Ad-miR-382.
Table S2. PCR Primer Sequences.
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