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Research Article

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Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

  1. Hitomi Tsuiji1,*,
  2. Yohei Iguchi2,†,
  3. Asako Furuya1,†,
  4. Ayane Kataoka1,
  5. Hiroyuki Hatsuta3,
  6. Naoki Atsuta2,
  7. Fumiaki Tanaka2,
  8. Yoshio Hashizume4,
  9. Hiroyasu Akatsu5,
  10. Shigeo Murayama3,
  11. Gen Sobue2,6,
  12. Koji Yamanaka1,6,7,8,*

Article first published online: 25 JAN 2013

DOI: 10.1002/emmm.201202303

Issue

EMBO Molecular Medicine

EMBO Molecular Medicine

Volume 5, Issue 2, pages 221–234, February 2013

Additional Information

How to Cite

Tsuiji, H., Iguchi, Y., Furuya, A., Kataoka, A., Hatsuta, H., Atsuta, N., Tanaka, F., Hashizume, Y., Akatsu, H., Murayama, S., Sobue, G. and Yamanaka, K. (2013), Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med, 5: 221–234. doi: 10.1002/emmm.201202303

Author Information

  1. 1

    Laboratory for Motor Neuron Disease, RIKEN Brain Science Institute, Wako, Saitama, Japan

  2. 2

    Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

  3. 3

    Department of Neuropathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi, Tokyo, Japan

  4. 4

    Department of Neuropathology, Fukushimura Hospital, Toyohashi, Aichi, Japan

  5. 5

    Choju Medical Institute, Fukushimura Hospital, Toyohashi, Aichi, Japan

  6. 6

    Japan Science and Technology Agency, CREST, Japan

  7. 7

    Brain Science Institute, Saitama University, Saitama, Japan

  8. 8

    Graduate School of Medicine, Kyoto University, Kyoto, Japan

  1. †

    These authors contributed equally to this work.

*Tel: +81 48 467 5467; Fax: +81 48 467 9725

  • †

    These authors contributed equally to this work.

Publication History

  1. Issue published online: 4 FEB 2013
  2. Article first published online: 25 JAN 2013
  3. Accepted manuscript online: 19 DEC 2012 02:30AM EST
  4. Manuscript Revised: 7 DEC 2012
  5. Manuscript Accepted: 7 DEC 2012
  6. Manuscript Received: 28 NOV 2012

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  • Funded Access

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