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Figure S1. Analysis of immune cells infiltrating bladder five days after tumour injection.

Figure S2. Necrotic MB49-I cells do not activate HY-specific T cells.

Figure S3. MB49 grows faster than MB49-I in vitro.

Figure S4. Decorin knockdown in MB49-I cells does not affect the nature of immune cells infiltrating the tumour.

Figure S5. Two additional independent analyses confirm that decorin is overexpressed in human MIBC as compared to NMIBC.

Figure S6. DCN mRNA level is not correlated to DCN DNA level in bladder tumours.

Figure S7. Gene ontology annotation enriched within genes correlated to DCN.

Figure S8. Decorin is not required for in vitro proliferation of TCCSUP, and promotes matrigel invasion by MB49 and MB49-I cells in vitro.

Figure S9. A specific DCN isoform is expressed by muscle cells in bladder.

Table S1. Genes with mRNA expression level correlated or anticorrelated to DCN expression level in human MIBC.

Table S2. Functional pathways and gene ontology annotations relative to biological processes significantly enriched in genes positively correlated with DCN in human MIBC.


Table S3. Affymetrix U133plus2.0 microarray data in 162 human bladder tumours and 4 normal samples, for genes correlated with DCN in MIBC (Pearson R > 0.5).

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