See also: R Kivelä et al (March 2014)
VEGF-B: a more balanced approach toward cardiac neovascularization?
Version of Record online: 12 FEB 2014
© 2014 The Authors.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
EMBO Molecular Medicine
Volume 6, Issue 3, pages 297–298, March 2014
How to Cite
Kupatt, C. and Hinkel, R. (2014), VEGF-B: a more balanced approach toward cardiac neovascularization?. EMBO Mol Med, 6: 297–298. doi: 10.1002/emmm.201303730
- Issue online: 7 MAR 2014
- Version of Record online: 12 FEB 2014
There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF-B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization.