See also: M Schäfer et al (April 2014)
The emerging role of Nrf2 in dermatotoxicology
Article first published online: 12 FEB 2014
© 2014 The Authors.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
EMBO Molecular Medicine
Volume 6, Issue 4, pages 431–433, April 2014
How to Cite
Tan, N. S. and Wahli, W. (2014), The emerging role of Nrf2 in dermatotoxicology. EMBO Mol Med, 6: 431–433. doi: 10.1002/emmm.201303797
- Issue published online: 2 APR 2014
- Article first published online: 12 FEB 2014
The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison-induced chloracne and metabolizing acquired dioxin-induced skin hamartomas or MADISH.