Intestinal absorption and biomagnification of organochlorines

Authors

  • Frank A.P.C. Gobas,

    Corresponding author
    1. School of Natural Resource and Environmental Management, Simon Fraser University, Burnaby, British Columbia, V5A 1S6 Canada
    • School of Natural Resource and Environmental Management, Simon Fraser University, Burnaby, British Columbia, V5A 1S6 Canada
    Search for more papers by this author
  • Jim R. McCorquodale,

    1. The Great Lakes Institute, University of Windsor, Windsor, Ontario, N9B 3P4 Canada
    Search for more papers by this author
  • G.D. Haffner

    1. The Great Lakes Institute, University of Windsor, Windsor, Ontario, N9B 3P4 Canada
    Search for more papers by this author

Abstract

Dietary uptake rates of several organochlorines from diets with different lipid contents were measured in goldfish (Carassius auratus) to investigate the mechanism of intestinal absorption and biomagnification of organic chemicals. The results suggest that intestinal absorption is predominantly controlled by chemical diffusion rather than lipid cotransport. Data for chemical uptake in human infants are presented to illustrate that biomagnification is caused by the digestion of food in the gastrointestinal tract. The findings are discussed in the context of two conflicting theories for the mechanism of biomagnification, and a mechanistic model is presented for the dietary uptake and biomagnification of organic chemicals in fish and mammals.

Ancillary