Effects of butyltin compounds on phagocytic activity of hemocytes from three marine bivalves

Authors

  • Nicole Bouchard,

    1. Département d'océanographie, Université du Québec à Rimouski, Rimouski, Québec, G5L 3A1, Canada
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  • Émilien Pelletier,

    Corresponding author
    1. Institut National de la Recherche Scientifique, INRS-Océanologie, 310 allée des Ursulines, Rimouski, Québec, G5L 3A1, Canada
    • Institut National de la Recherche Scientifique, INRS-Océanologie, 310 allée des Ursulines, Rimouski, Québec, G5L 3A1, Canada
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  • Michel Fournier

    1. TOXEN, Université du Québec à Montréal, Québec, H3C 3P8, Canada
    2. Fisheries and Oceans Canada, Institute Maurice–Lamontagne, CP 1000 Mont-Joli, Québec, G5H 3Z4, Canada
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Abstract

Effects of tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) on the in vitro phagocytic activity of hemocytes from three marine bivalve species, Mytilus edulis, Mya arenaria, and Mactromeris polynyma, were determined using flow cytometry. Phagocytosis was reduced with increasing doses of TBT and DBT. The toxicity of butyltins on hemocytes decreased in the order DBT > TBT > MBT, and comparison of the relative sensitivity of the three species showed that blue mussels (M. edulis) were more tolerant of butyltin compounds than both clam species. Toxicity mechanisms of butyltins are discussed and compared to those of other metals.

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