Influence of deltamethrin on nonspecific cellular and humoral defense mechanisms in rainbow trout (Oncorhynchus mykiss)

Authors

  • Andrzej K. Siwicki,

    Corresponding author
    1. Department of Infection Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn-Kortowo II, Poland
    2. Department of Fish Pathology and Immunology, Inland Fisheries Institute in Olsztyn, 10-719 Olsztyn-Kortowo, Poland
    • Department of Infection Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn-Kortowo II, Poland.
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  • Elzbieta Terech-Majewska,

    1. Department of Infection Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn-Kortowo II, Poland
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  • Joanna Grudniewska,

    1. Department of Fish Pathology and Immunology, Inland Fisheries Institute in Olsztyn, 10-719 Olsztyn-Kortowo, Poland
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  • Joanna Malaczewska,

    1. Department of Infection Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn-Kortowo II, Poland
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  • Krzysztof Kazun,

    1. Department of Fish Pathology and Immunology, Inland Fisheries Institute in Olsztyn, 10-719 Olsztyn-Kortowo, Poland
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  • Agnieszka Lepa

    1. Department of Fish Pathology and Immunology, Inland Fisheries Institute in Olsztyn, 10-719 Olsztyn-Kortowo, Poland
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  • Presented at the 1st International Workshop on Aquatic Toxicology and Biomonitoring, Vodnany, Czech Republic, August 27–29, 2008.

Abstract

The influence of deltamethrin on the innate immunity in rainbow trout was examined. Fish were immersed in deltamethrin at doses of 1, 2, and 4 µg/L for 30 min. The results showed that deltamethrin at doses of 2 and 4 µg/L decreased phagocytic activity of spleen macrophages and proliferative response of pronephros lymphocytes at days 1, 2, and 5 after immersion. Deltamethrin at these doses decreased the lysozyme activity, total protein, and immunoglobulin levels in serum. The greatest immunosuppressive influence of deltamethrin at dose 4 µg/L was observed at the end of the study. Environ. Toxicol. Chem. 2010;29:489–491. © 2009 SETAC

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