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Morphant technology in model developmental systems
Article first published online: 23 JUL 2001
DOI: 10.1002/gene.1038
Copyright © 2001 Wiley-Liss, Inc.
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How to Cite
Ekker, S. C. and Larson, J. D. (2001), Morphant technology in model developmental systems. Genesis, 30: 89–93. doi: 10.1002/gene.1038
Publication History
- Issue published online: 23 JUL 2001
- Article first published online: 23 JUL 2001
- Manuscript Received: 14 JUN 2001
- Manuscript Accepted: 14 JUN 2001
Funded by
- National Institutes of Health
LITERATURE CITED
- , , , , , , , . 2000. c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity. J Pharmacol Exp Ther 292: 921–928.
- , , , , . 2001. The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128: 849–858.
- , , , . 2001. Inhibition of skiA and skiB gene expression ventralizes zebrafish embryo. Genesis 30: xxx–xxx.Direct Link:
- , , , . 2000. Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages. Nucleic Acids Res 28: 2153–2157.
- , , . 2001. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30: xxx–xxx.Direct Link:
- , , , , , , , , , , , . 1996. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123: 37–46.
- , . 2001. Fish x 3. Nat Genet 27: 8–9.
- . 2000. Morphants: a new systematic vertebrate functional genomics approach. Yeast 17: 302–306.Direct Link:
- , , , , , , , , , , , , , , , , . 1996. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123: 1–36.
- , , . 2000. β-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach. Dev Biol 222: 124–134.
- , , , , . 2001. SpKrl: a direct target of β-catenin regulation required for endoderm differentiation in sea urchin embryos. Development 128: 365–375.
- , , , . 2001. The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 128: 1467–1479.
- , , . 2001. Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick and pipetail mutations. Genesis 30: xxx–xxx.Direct Link:
- , . 2000. Effective targeted gene knockdown in zebrafish. Nat Genet 26: 216–220.
- , . 2001. The zebrafish as a novel system for functional genomics and therapeutic development applications. Curr Opinion Mol Ther 3(3): 224–228.
- , , . 2000. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 17: 294–301.Direct Link:
- , , , , , . 1996. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev 6: 169–175.
- , , , , . 2000. In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alpha. Antisense Nucleic Acid Drug Dev 10: 11–16.
- , , , , , . 1998. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development 125: 2983–2993.
- , , . 1999. Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake. J Biol Chem 274: 21783–21789.
- , . 2001. Xenopus frizzled-7 morphant displays defects in dorso-ventral patterning and convergent extension movements during gastrulation. Genesis 30: xxx–xxx.Direct Link:
- , , , . 2001. Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis 30: xxx–xxx.Direct Link:
- . 1999. Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim Biophys Acta 1489: 141–158.

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