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Pdx-1 knockdown reduces insulin promoter activity in zebrafish
Article first published online: 23 JUL 2001
DOI: 10.1002/gene.1048
Copyright © 2001 Wiley-Liss, Inc.
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How to Cite
Huang, H., Liu, N. and Lin, S. (2001), Pdx-1 knockdown reduces insulin promoter activity in zebrafish. Genesis, 30: 134–136. doi: 10.1002/gene.1048
Publication History
- Issue published online: 23 JUL 2001
- Article first published online: 23 JUL 2001
- Manuscript Accepted: 12 JUN 2001
- Manuscript Received: 29 MAR 2001
LITERATURE CITED
- , , . 1996. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122: 1409–1416.
- , , . 1999. Early appearance of pancreatic hormone-expressing cells in the zebrafish embryo. Mech Dev 87: 217–221.
- , , , , , . 2001. Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Dev Biol 230: 189–203.
- , , , , . 2001. Analysis of pancreatic development in living transgenic zebrafish embryos. Mol Cell Endocrinol 117: 117–124.
- , , , . 1994. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371: 606–609.
- , , , . 1998. Conservation of PDX-1 structure, function, and expression in zebrafish. Endocrinology 139: 1440–1449.
- , . 2000. Effective targeted gene ‘knockdown’ in zebrafish. Nat Genet 26: 216–220.
- , , , , , , , . 1996. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122, 983-95.
- , , . 1993. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12: 4251–4259.
- , , , , . 1994. Insulin expression in pancreatic islet cels relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol 8: 1798–1806.
- , , , , , . 1994. XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol 8: 806–816.
- , . 1997. The beta cell transcription factors and development of the pancreas. J Mol Med 75: 327–340.
- , , , , , , , . 1995. The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. Biochem J 310: 997–1003.
- , . 1968. Ultrastructural studies of early morphogenesis and cytodifferentiation in the embryonic mammalian pancreas. Dev Biol 17: 413–446.