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Zebrafish hhex regulates liver development and digestive organ chirality

  1. Kenneth N. Wallace1,†,
  2. Shamila Yusuff1,†,
  3. Jennifer M. Sonntag3,
  4. Alvin J. Chin2,3,
  5. Michael Pack1,*

Article first published online: 23 JUL 2001

DOI: 10.1002/gene.1050

Issue

genesis

genesis

Volume 30, Issue 3, pages 141–143, July 2001

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How to Cite

Wallace, K. N., Yusuff, S., Sonntag, J. M., Chin, A. J. and Pack, M. (2001), Zebrafish hhex regulates liver development and digestive organ chirality. Genesis, 30: 141–143. doi: 10.1002/gene.1050

Author Information

  1. 1

    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

  2. 2

    Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

  3. 3

    Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania

  1. †

    These authors contributed equally to this work.

*Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104

Publication History

  1. Issue published online: 23 JUL 2001
  2. Article first published online: 23 JUL 2001
  3. Manuscript Accepted: 11 JUN 2001
  4. Manuscript Received: 4 MAY 2001

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LITERATURE CITED

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  • Chin AJ, Tsang M, Weinberg ES. 2000. Heart and gut chiralities are controlled independently from initial heart position in the developing zebrafish. Dev Biol 227: 403–421.
  • Denson LA, Karpen SJ, Bogue CW, Jacobs HC. 2000. Divergent homeobox gene hex regulates promoter of the Na(+)-dependent bile acid cotransporter. Am J Physiol Gastrointest Liver Physiol 279: G347–355.
  • Ho CY, Houart C, Wilson SW, Stainier DY. 1999. A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene. Curr Biol 9: 1131–1134.
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  • Liao W, Ho CY, Yan YL, Postlethwait J, Stainier DY. 2000. Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127: 4303–4313.
  • Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS. 2000. The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development 127: 2433–2445.
  • Tanaka T, Inazu T, Yamada K, Myint Z, Keng VW, Inoue Y, Taniguchi N, Noguchi T. 1999. cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the protein. Biochem J 339: 111–117.
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