Article

You have free access to this content

Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations

  1. Zsolt Lele†,
  2. Jeroen Bakkers†,
  3. Matthias Hammerschmidt*

Article first published online: 23 JUL 2001

DOI: 10.1002/gene.1063

Issue

genesis

genesis

Volume 30, Issue 3, pages 190–194, July 2001

Additional Information

How to Cite

Lele, Z., Bakkers, J. and Hammerschmidt, M. (2001), Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations. Genesis, 30: 190–194. doi: 10.1002/gene.1063

Author Information

  1. Hans-Spemann Laboratory, Max-Planck Institut für Immunbiologie, Freiburg, Germany

  1. †

    Joint first authors

*Hans-Spemann-Laboratorium, Max-Planck Institut für Immunbiologie, Stuebeweg 51, D-79108 Freiburg, Germany

Publication History

  1. Issue published online: 23 JUL 2001
  2. Article first published online: 23 JUL 2001
  3. Manuscript Accepted: 12 JUN 2001
  4. Manuscript Received: 8 MAY 2001

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (296K)

LITERATURE CITED

  • Bauer H, Lele Z, Rauch G-J, Geisler R, Hammerschmidt M. 2001. The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/Bmp7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128: 849–858.
  • Blader P, Rastegar S, Fischer N, Strähle U. 1997. Cleavage of the BMP-4 antagonist Chordin by zebrafish Tolloid. Science 278: 1937–1940.
  • Blader P, Strähle U, Ingham PW. 1996. Three Wnt genes expressed in a wide variety of tissues during development of the zebrafish, Danio rerio: developmental and evolutionaly perspectives. Dev Genes Evol 206: 3–13.
  • Connors SA, Trout J, Ekker M, Mullins MC. 1999. The role of tolloid/minifin in dorsoventral pattern formation of the zebrafish embryo. Development 126: 3119–3130.
  • Dick A, Hild M, Bauer H, Imai Y, Maifeld H, Schier A, Talbot W, Bowemeester T, Hammerschmidt M. 2000. Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. Development 127: 343–354.
  • Fisher S, Amacher SL, Halpern ME. 1997. Loss of cerebrum function ventralizes the zebrafish embryo. Development 124: 1301–1311.
  • Hammerschmidt M, Blader P, Strähle U. 1999. Strategies to perturb zebrafish development. Methods Cell Biol. 59: 87–115.
  • Hammerschmidt M, Pelegri F, Mullins MC, Kane DA, Brand M, van Eeden FJM, Furutani-Seiki M, Granato M, Haffter P, Heisenberg C-P, Jiang Y-J, Kelsh RN, Odenthal J, Warga RM, Nüsslein-Volhard C. 1996. Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development 123: 143–151.
  • Heisenberg C-P, Nüsslein-Volhard C. 1997. The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol 184: 85–94.
  • Heisenberg C-P, Tada M, Rauch G-J, Saude L, Concha ML, Geisler R, Stemple DL, Smith JC, Wilson SW. 2000. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405: 76–81.
  • Hild M, Dick A, Rauch JG, Meier A, Bouwmeester T, Haffter P, Hammerschmidt M. 1999. The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo. Development 126: 2149–2159.
  • Kishimoto Y, Lee K-H, Zon L, Hammerschmidt M, Schulte-Merker S. 1997. The molecular nature of swirl: BMP2 function is essential during early dorsoventral patterning. Development 124: 4457–4466.
  • Krauss S, Johansen T, Korzh V, Fjose A. 1991. Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis. Development 113: 1193–1206.
  • Li Y, Allende ML, Finkelstein R, Weinberg ES. 1994. Expression of two zebrafish orthodenitcle-related genes in the embryonic brain. Mech Dev 48: 229–244.
  • Makita R, Mizuno T, Koshida S, Kuroiwa A, Takeda H. 1998. Zebrafish wnt11: pattern and regulation of the expression by the yolk cell and No tail activity. Mech Dev 71: 165–176.
  • Mintzer K, Lee MA. Runke G, Trout J, Whitman M, Mullins M. 2001. lost-a-fin encodes a typ I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation. Development 128: 859–869.
  • Mullins MC, Hammerschmidt M, Kane DA, Odenthal J, Brand M, van Eeden FJM, Furutani-Seiki M, Granato M, Haffter P, Heisenberg C-P, Jiang Y-J, Kelsh RN, Nüsslein-Volhard C. 1996. Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123: 81–93.
  • Nasevicius A, Ekker SC. 2000. Effective targeted gene knockdown in zebrafish. Nature Genet. 26: 216–220.
  • Nguyen VH, Schmid B, Trout J, Conners SA, Ekker M, Mullins MC. 1998. Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev Biol 199: 93–110.
  • Oxtoby E, Jowett T. 1993. Cloning of the zebrafish Krox-20 (Krx-20) and its expression during hindbrain development. Nucleic Acids Res 21: 1087–1095.
  • Piotrowski T, Schilling TF, Brand M, Jiang Y-J, Heisenberg C-P, Beuchle D, Grandel H, van Eeden FJM, Furutani-Seiki M, Granato M, Haffter P, Hammerschmidt M., Kane DA, Kelsh RN, Mullins MC, Odenthal J, Warga RM, Nüsslein-Volhard C. 1996. Jaw and the branchial arch mutants in the zebrafish II: anterior arches and cartilage differentiation. Development 123: 345–356.
  • Rauch G-J, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. 1997. WNT5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor Symp Quant Biol 62: 227–233.
  • Schmid B, Fürthauer M, Conners SA, Trout J, Thisse B, Thisse C, Mullins MC. 2000. Equivalent genetic roles of bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. Development 127: 957–967.
  • Schulte-Merker S, Lee LJ, McMahon AP, Hammerschmidt M. 1997. The zebrafish organizer requires chordino. Nature 387: 862–863.
  • Solnica-Krezel L, Stemple DL, Mountcastle-Shah E, Rangini Z, Neuhauss SCF, Malicki J, Schier A, Stanier DYR, Zwartkruis F, Abdelilah S, Driever W. 1996. Mutations affecting cell fates and cellular rearrangements during gastrulation in the zebrafish. Development 123: 67–80.
Get PDF (296K)