Autoantibodies to pancreatic islet cells and insulin in IDDM families: The GAW5 data

Authors

  • Noel K. Maclaren,

    1. Department of Pathology, University of Florida College of Medicine, Gainesville, Florida
    2. Diabetes Research Institute, Düsseldorf, Federal Republic of Germany
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  • William J. Riley,

    1. Department of Pathology, University of Florida College of Medicine, Gainesville, Florida
    2. Diabetes Research Institute, Düsseldorf, Federal Republic of Germany
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  • David K. McCulloch,

    1. Diabetes Research Institute, Düsseldorf, Federal Republic of Germany
    2. Diabetes Endocrinology Research Center, Pacific Medical Center, University of Washington, Seattle
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  • Dr. Jerry P. Palmer

    Corresponding author
    1. Diabetes Research Institute, Düsseldorf, Federal Republic of Germany
    2. Diabetes Endocrinology Research Center, Pacific Medical Center, University of Washington, Seattle
    • Diabetes Research Center, Pacific Medical Center—Qtrs. 8/9, 1200 12th Ave. S., Seattle, WA 98144

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Abstract

Antibodies to pancreatic islet cells and insulin were studied in the Genetic Analysis Workshop 5 (GAW5) families, as indicators of an autoimmune component of pathogenesis. The rationale for these studies is summarized briefly, and references to the laboratory methods used are provided.

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