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Keywords:

  • statistical genetics;
  • segregation analysis;
  • linkage analysis

Abstract

The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set of methods are evaluated with regard to the success with which they were able to determine the mode of inheritance and locate the genes underlying an oligogenically determined disease and four related quantitative traits. © 1995 Wiley-Liss, Inc.