A graphical approach for presenting linkage results from a genomic screen

Authors

  • Elizabeth W. Pugh,

    1. Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, LA
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  • Diptasri M. Mandal,

    1. Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, LA
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  • Dr. Alexander F. Wilson

    Corresponding author
    1. Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, LA
    • NCHGR, NIH, 49 Convent Drive, MSC 4470, Building 49, Room 4A22, Bethesda, MD 20892-4470

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Abstract

Initially, a sib-pair linkage analysis was performed between the marker loci and six untransformed variables. Results from several variations of this initial analysis were compared using a graphical approach (P-plots) to simplify presentation. When results were compared to the generating model, most of the aspects of the generating model were recovered, although we did not find evidence of the polygenic component shared by Q2 and Q3, or evidence of linkage between MG4 and Q4 at the 0.01 level. © 1995 Wiley-Liss, Inc.

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