Genetic Epidemiology with a Capital E: Where Will We Be in Another 10 Years?
Article first published online: 6 FEB 2012
© 2012 Wiley Periodicals, Inc.
Volume 36, Issue 3, pages 179–182, April 2012
How to Cite
Thomas, D. C. (2012), Genetic Epidemiology with a Capital E: Where Will We Be in Another 10 Years?. Genet. Epidemiol., 36: 179–182. doi: 10.1002/gepi.21612
- Issue published online: 19 APR 2012
- Article first published online: 6 FEB 2012
- Manuscript Accepted: 9 DEC 2011
- Manuscript Received: 15 NOV 2011
- genome-wide association studies;
- next-generation sequencing;
- genetic testing;
- translational research;
- integrative genomics
In a commentary on the evolution of the field of genetic epidemiology over the past 10 years, Khoury et al. (2011) highlight several important developments, including the emergence of evaluation of genetic discoveries for their translational utility and of standards for reporting genetic findings. In this companion to their article, I reflect on some of these trends and speculate about the direction of the field in the future. In particular, I emphasize the opportunities posed by novel technologies like next-generation sequencing and the biological insights emerging from integrative genomics, but I also question the utility of large consortia. The basic principles of population-based research and the importance of taking account of the environment remain important to the field.