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gepi21668-sup-0001-FigureS1.tif2111KFigure 1. Genotype relative risks at causal variant C (GRRC) that result in 5% power to detect association (p < 5×10−8) at genotyped variant M using n cases and n controls. We assume disease prevalence 10% and D′ = 0.6 and 0.8 between M and C.
gepi21668-sup-0002-FigureS2.tif2111KFigure 2. T2D linkage maximum LOD scores (MLS) at the loci identified in T2D association analyses. The x-axis is the risk allele frequency (RAFM) of T2D-associated SNPs.
gepi21668-sup-0003-FigureS3.tif2346KFigure 3.
gepi21668-sup-0004-TableS1.doc152KTable 1. T2D susceptibility loci detected with common variants. RAFC is a lower bound at which there is 5% or 50% power to detect association at observed p-value at marker M in a GWAS of the given effective sample size, and 95% or 80% power to detect linkage at the observed MLS value given 4,200 ASPs.

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