Additional Supporting Information may be found in the online version of this article.

GLIA_21245_sm_SuppFig1.tiff3042KSupporting Information Figure 1. Scheme of the mevalonate pathway. Zaragozic Acid A (Zara) ia a potent inhibitor of squalene synthase which results in inhibiting cholesterol biosynthesis but not isoprenylation. Specific inhibitors of the isoprenylation pathway included GGTI-2133: inhibitor of geranylgeranyltransferase, and FTI-277: inhibitor of farnesyltransferase.
GLIA_21245_sm_SuppTab1.doc56KSupporting Information Table 1. Donor specifications
GLIA_21245_sm_SuppTab2A.doc54KSupporting Information Table 2A. TLR2-induced cytokine/chemokine and growth factor levels in microglia from different donors.
GLIA_21245_sm_SuppTab2B.doc39KSupporting Information Table 2B. TLR2, 3, 4 and 8-induced cytokine/chemokine and growth factor levels in microglia from donor N90.

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