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Additional Supporting Information may be found in the online version of thisarticle.

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GLIA_22367_sm_SuppInfoFig1.pdf104KSupporting Information Figure 1. (A) shows the white matter part, (B) the grey matter part of a HE-stained chronic-active leucocortical lesion. Note distinct perivascular infiltration in the white but not the grey matter part (arrow). (C) shows the white matter part, (D) the grey matter part of an anti CD3-stained chronic-active leucocortical lesion. Note the high number of CD3-expressing lymphocytes in the perivascular compartment within the white but not the grey matter part (arrowhead). (E) shows the NAGM, (F) the grey matter border of an anti-GFAP stained chronic-active leucocortical lesion. (G) shows the NAWM, (H) the white matter border of an anti-GFAP stained chronic-active leucocortical lesion. Note distinct astrocytosis in both parts of the lesion. Scale bars: 250μm (A-D), 50μm (E-H)

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