Tim Clarner and Felix Diederichs contributed equally as first authors. Sandra Amor and Markus Kipp contributed equally as last authors.
Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions†
Article first published online: 11 JUN 2012
Copyright © 2012 Wiley Periodicals, Inc.
Volume 60, Issue 10, pages 1468–1480, October 2012
How to Cite
Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., van der Valk, P., Beyer, C., Amor, S. and Kipp, M. (2012), Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia, 60: 1468–1480. doi: 10.1002/glia.22367
- Issue published online: 16 AUG 2012
- Article first published online: 11 JUN 2012
- Manuscript Accepted: 14 MAY 2012
- Manuscript Revised: 9 MAY 2012
- Manuscript Received: 31 JUL 2011
- START grants of the Medical Faculty, RWTH Aachen
- The Deutsche Forschungsgemeinschaft
- B. Braun Melsungen Stiftung, Stichting MS Research and the MS Society of Great Britain and Northern Ireland
Additional Supporting Information may be found in the online version of thisarticle.
|GLIA_22367_sm_SuppInfoFig1.pdf||104K||Supporting Information Figure 1. (A) shows the white matter part, (B) the grey matter part of a HE-stained chronic-active leucocortical lesion. Note distinct perivascular infiltration in the white but not the grey matter part (arrow). (C) shows the white matter part, (D) the grey matter part of an anti CD3-stained chronic-active leucocortical lesion. Note the high number of CD3-expressing lymphocytes in the perivascular compartment within the white but not the grey matter part (arrowhead). (E) shows the NAGM, (F) the grey matter border of an anti-GFAP stained chronic-active leucocortical lesion. (G) shows the NAWM, (H) the white matter border of an anti-GFAP stained chronic-active leucocortical lesion. Note distinct astrocytosis in both parts of the lesion. Scale bars: 250μm (A-D), 50μm (E-H)|
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