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Research Article
Occurrence and risk factors of mild cognitive impairment in the older Chinese population: a 3-year follow-up study
Article first published online: 13 SEP 2011
DOI: 10.1002/gps.2768
Copyright © 2011 John Wiley & Sons, Ltd.
Additional Information
How to Cite
Hai, S., Dong, B., Liu, Y. and Zou, Y. (2012), Occurrence and risk factors of mild cognitive impairment in the older Chinese population: a 3-year follow-up study. Int. J. Geriat. Psychiatry, 27: 703–708. doi: 10.1002/gps.2768
Publication History
- Issue published online: 11 JUN 2012
- Article first published online: 13 SEP 2011
- Manuscript Accepted: 28 JUN 2011
- Manuscript Received: 10 JAN 2011
- Abstract
- Article
- References
- Cited By
Keywords:
- cognitive impairment;
- occurrence;
- risk factor;
- dementia
Objective
To investigate the occurrence and risk factors of mild cognitive impairment (MCI) and the conversion rates to dementia in Chinese people over 80 years of age.
Methods
Two hundred and two participants (>80 years old) without dementia were assessed clinically using neuropsychological tests; they were re-assessed at 1, 2, and 3 years.
Results
The results revealed that 30.2% of the study population was classified as having MCI at baseline. Multivariate linear regression analysis showed that coronary heart disease, hypertension, and stroke were risk factors of MCI. During the 3 years follow-up, the occurrence of MCI increased, and 21.8% of the participants with MCI progressed to dementia.
Conclusions
These results suggest that in the older elderly, prevention and early treatment of cardiovascular and cerebrovascular diseases may be effective in lowering the risk of MCI. MCI is a high risk factor for dementia. Copyright © 2011 John Wiley & Sons, Ltd.