Screening for DSM-IV-TR cognitive disorder NOS in Parkinson's disease using the Mattis Dementia Rating Scale
Article first published online: 24 MAY 2012
Copyright © 2012 John Wiley & Sons, Ltd.
International Journal of Geriatric Psychiatry
Volume 28, Issue 4, pages 364–371, April 2013
How to Cite
Pontone, G. M., Palanci, J., Williams, J. R. and Bassett, S. S. (2013), Screening for DSM-IV-TR cognitive disorder NOS in Parkinson's disease using the Mattis Dementia Rating Scale. Int. J. Geriat. Psychiatry, 28: 364–371. doi: 10.1002/gps.3833
- Issue published online: 6 MAR 2013
- Article first published online: 24 MAY 2012
- Manuscript Accepted: 24 APR 2012
- Manuscript Received: 19 MAR 2012
- NIH grants. Grant Numbers: R01-MH069666, NIH-P50-NS-58377, NIH-5T32-AG-027668-02
- Morris K. Udall Parkinson's Disease Research Center of Excellence at Johns Hopkins
- Age-Related Cognitive Disorders Training Grant
- Parkinson's disease;
- non-motor symptoms;
- cognitive impairment;
- cognitive screening;
- Dementia Rating Scale
This study explores the utility of the Mattis Dementia Rating Scale (MDRS) as a screening tool for the Diagnostic and Statistical Manual for Mental Disorders 4th edition (DSM-IV-TR) diagnosis cognitive disorder not otherwise specified (NOS) in Parkinson's disease (PD).
A total of 125 individuals with PD were diagnosed using DSM-IV-TR criteria for cognitive disorder NOS and dementia. Receiver operating characteristics (ROC) tested the discriminant validity of the MDRS, with the clinician's diagnosis serving as the gold standard.
The MDRS ROC curve to discriminate subjects with cognitive disorder NOS from non-demented subjects had an area under the curve of 0.59 (standard error = 0.08, 95% CI: 0.43–0.74).
The MDRS is not effective for identifying PD patients with cognitive disorder NOS without dementia. Copyright © 2012 John Wiley & Sons, Ltd.