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Value of EQ-5D in Mexican city older population with and without dementia (SADEM study)

Authors

  • Rosalinda Sanchez-Arenas,

    1. Neurological Diseases Research Unit, Specialty Hospital, National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico
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  • Gilberto Vargas-Alarcon,

    1. Department of Molecular Biology and Cardiovascular Disease's Genomic and Proteomic Study Group, National Institute of Cardiology Ignacio Chávez, National Institutes of Health, Mexico City, Mexico
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  • Sergio Sanchez-Garcia,

    1. Epidemiologic and Health Service Research Unit, Aging Area, Mexican Institute of Social Security, Mexico City, Mexico
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  • Carmen Garcia-Peña,

    1. Epidemiologic and Health Service Research Unit, Aging Area, Mexican Institute of Social Security, Mexico City, Mexico
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  • Lidia Gutierrez-Gutierrez,

    1. Department of Neurology and Psychiatry, National Institute of Medical Sciences and Nutrition “Salvador Zubirán”, National Institutes of Health, Mexico City, Mexico
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  • Israel Grijalva,

    1. Neurological Diseases Research Unit, Specialty Hospital, National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico
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  • Angelica Garcia-Dominguez,

    1. Epidemiologic and Health Service Research Unit, Aging Area, Mexican Institute of Social Security, Mexico City, Mexico
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  • Teresa Juárez-Cedillo

    Corresponding author
    1. Epidemiologic and Health Service Research Unit, Aging Area, Mexican Institute of Social Security, Mexico City, Mexico
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Abstract

Background

The EuroQoL-5D (EQ-5D) is a brief, multi-attribute, preference-based health status measurement. The objective of this study was to assess the validity and reliability of EQ-5D in older adults with and without dementia in Mexico City.

Methods

The Study on Aging and Dementia in Mexico (SADEM) was a survey of 3101, Mexican adults (60 + years old). An in-home face-to-face interview was administered. EQ-5D using ranking to rate states on a 100-point visual analogue scale; Daily Living Activities (ADL), Instrumental Activities of Daily Living (IADL), Mini Mental State Examination (MMSE), Short Form of the quality of life survey (SF-36), and Charlson comorbility index were used for comparison. The validity and reliability of EQ-5D were tested. We identified states of health for direct valuation; state 11111 (“no problems”) had to be included because it was essential to the reseating (onto a 0–1 scale) of the visual analogue scale data. We included all plausible combinations of levels across each of the five EQ-5D dimensions and evaluated any significant interaction effects and factorial designs, based on balanced complete blocks.

Results

The EQ-5D was applied to 3101 older people, of whom 109 (3.4%) had dementia. The general reliability of EQ-5D for cases was 0.80 and for controls 0.76, for each dimension. We had a total of 103 combinations for controls and 45 for cases. The percentage for the state of health “no problems” (11111) for controls was 30.4%, and had the highest percentage of cases (8.8%).

Conclusion

The resulting valuations form the basis for clinical use and facilitate the interpretation and evaluation of health care. Copyright © 2013 John Wiley & Sons, Ltd.

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