Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly
Article first published online: 19 SEP 2001
Copyright © 2001 John Wiley & Sons, Ltd.
International Journal of Geriatric Psychiatry
Volume 16, Issue 9, pages 873–878, September 2001
How to Cite
Hultberg, B., Isaksson, A., Nilsson, K. and Gustafson, L. (2001), Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly. Int. J. Geriat. Psychiatry, 16: 873–878. doi: 10.1002/gps.439
- Issue published online: 19 SEP 2001
- Article first published online: 19 SEP 2001
- Manuscript Accepted: 21 DEC 2000
- Manuscript Received: 6 SEP 2000
- methylmalonic acid;
- psychogeriatric patients
Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction. Copyright © 2001 John Wiley & Sons, Ltd.