The cognitive drug research computerized assessment system in the evaluation of early dementia-is speed of the essence?
Version of Record online: 13 OCT 2004
Copyright © 1995 John Wiley & Sons, Ltd.
International Journal of Geriatric Psychiatry
Volume 10, Issue 3, pages 199–206, March 1995
How to Cite
Nicholl, C. G., Lynch, S., Kelly, C. A., White, L., Simpson, P. M., Wesnes, K. A. and Pitt, B. M. N. (1995), The cognitive drug research computerized assessment system in the evaluation of early dementia-is speed of the essence?. Int. J. Geriat. Psychiatry, 10: 199–206. doi: 10.1002/gps.930100306
- Issue online: 13 OCT 2004
- Version of Record online: 13 OCT 2004
- Manuscript Accepted: 4 AUG 1994
- Manuscript Received: 5 APR 1994
- Memory clinic;
- age associated memory impairment;
- computerized assessment of cognitive function
The cognitive drug research computerized assessment system (COGDRAS) was evaluated in 98 unselected Hammer-smith Hospital Memory Clinic patients (mean age 64.9, range 28-83 years). They were divided into five groups (worried well, depressed, demented, minimally cognitively impaired and other brain disorders) on clinical assessment, Mini Mental State Examination (MMSE) and Cambridge Cognitive Examination (CAMCOG) scores. All but one patient completed the computer package, confirming its acceptability. The results of the COGDRAS in the five groups were analysed blind to diagnosis. The performance of the demented group was significantly impaired in comparison with the worried well group, showing that the COGDRAS is valid in mild dementia (mean MMSE 21.5, mean CAMCOG 73.9). The depressed group tended to perform slightly less well than the worried well, and the ‘other’ group showed a wide range of scores consistent with its diversity. The minimally impaired had scores intermediate between the demented and worried well, but an interesting speed/accuracy tradeoff was seen-patients appeared to maintain accuracy by taking longer to perform tasks. The heterogeneity of the minimally impaired group and the role of the measurement of task completion time in the diagnosis of early dementia are discussed.