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Modality independence of word comprehension

Authors

  • James R. Booth,

    Corresponding author
    1. Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois
    2. Department of Radiology, Evanston Hospital, Evanston, Illinois
    3. Cognitive Brain Mapping Group, Northwestern University, Chicago, Illinois
    • Department of Communication Sciences and Disorders, Northwestern University, 2299 North Campus Drive, Evanston, Illinois, 60208-3560
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  • Douglas D. Burman,

    1. Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois
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  • Joel R. Meyer,

    1. Department of Radiology, Evanston Hospital, Evanston, Illinois
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  • Darren R. Gitelman,

    1. Cognitive Brain Mapping Group, Northwestern University, Chicago, Illinois
    2. Department of Neurology, Northwestern University Medical School, Chicago, Illinois
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  • Todd B. Parrish,

    1. Cognitive Brain Mapping Group, Northwestern University, Chicago, Illinois
    2. Department of Radiology, Northwestern University Medical School, Chicago, Illinois
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  • M. Marsel Mesulam

    1. Cognitive Brain Mapping Group, Northwestern University, Chicago, Illinois
    2. Department of Neurology, Northwestern University Medical School, Chicago, Illinois
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Abstract

Functional magnetic resonance imaging (fMRI) was used to examine the functional anatomy of word comprehension in the auditory and visual modalities of presentation. We asked our subjects to determine if word pairs were semantically associated (e.g., table, chair) and compared this to a reference task where they were asked to judge whether word pairs rhymed (e.g., bank, tank). This comparison showed task-specific and modality-independent activation for semantic processing in the heteromodal cortices of the left inferior frontal gyrus (BA 46, 47) and left middle temporal gyrus (BA 21). There were also modality-specific activations in the fusiform gyrus (BA 37) for written words and in the superior temporal gyrus (BA 22) for spoken words. Our findings are consistent with the hypothesis that word form recognition (lexical encoding) occurs in unimodal cortices and that heteromodal brain regions in the anterior as well as posterior components of the language network subserve word comprehension (semantic decoding). Hum. Brain Mapping 16:251–261, 2002. © 2002 Wiley-Liss, Inc.

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