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HBM_20673_sm_suppinfotable.doc227KTable 2. List of brain regions in each component identified during ‘resting state’ fMRI. All regions surpass corrections for multiple comparisons (p < .000001 FDR) in SPM2 one-sample t test.
HBM_20673_sm_suppinfofigure1.doc208KFig. 1. This is a sample causal connectivity graph for n=100 participants created using tools published by Seth (2005) to examine Granger Causality among the 13 ‘resting state’ fMRI neural network time courses we examined in this study. Each node is labeled using the component number generated from the ICA analysis. Red paths denote significant (p < .001) bidirectional paths while green paths indicate significant unidirectional connections. The thickness of each path represents the relative strength of each causal connection. As noted above in the response to Rev #1, Comment 10, this type of figure cannot usefully convey information about adolescent and adult differences in system causal relationships. Not only are there too many nodes to make the figure graphically appealing and clearly interpretable, but also the type of information represented does not lend itself to conveying specific age-related findings. We favor Manuscript Figure 3 to present these findings.

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