Tilo Kircher and Katharina Sass contributed equally to this work.
Priming words with pictures: Neural correlates of semantic associations in a cross-modal priming task using fMRI
Article first published online: 15 JUN 2009
Copyright © 2009 Wiley-Liss, Inc.
Human Brain Mapping
Volume 30, Issue 12, pages 4116–4128, December 2009
How to Cite
Kircher, T., Sass, K., Sachs, O. and Krach, S. (2009), Priming words with pictures: Neural correlates of semantic associations in a cross-modal priming task using fMRI. Hum. Brain Mapp., 30: 4116–4128. doi: 10.1002/hbm.20833
- Issue published online: 17 NOV 2009
- Article first published online: 15 JUN 2009
- Manuscript Revised: 5 MAY 2009
- Manuscript Accepted: 5 MAY 2009
- Manuscript Received: 30 JUL 2008
- Interdisciplinary Center for Clinical Research “BIOMAT,” RWTH Aachen University. Grant Number: IZKF VV N68
- semantic priming;
- lexical decision;
- semantic processing;
In our everyday life we process information from different modalities simultaneously with great ease. With the current study we had the following goals: to detect the neural correlates of (1) automatic semantic processing of associates and (2) to investigate the influence of different visual modalities on semantic processing. Stimuli were presented with a short SOA (350 ms) as subjects performed a lexical decision task. To minimize the variance and increase homogeneity within our sample, only male subjects were measured. Three experimental conditions were compared while brain activation was measured with a 3 T fMRI scanner: related word-pairs (e.g., frame–picture), unrelated word-pairs (e.g., frame–car) as well as word-nonword pairs (e.g., frame–fubber). They were presented uni- (word -word) and cross-modally (picture–word). Behavioral data revealed a priming effect for cross-modal and unimodal word-pairs. On a neural level, the unimodal condition revealed response suppression in bilateral fronto-parietal regions. Cross-modal priming led to response suppression within the right inferior frontal gyrus. Common areas of deactivation for both modalities were found in bilateral fronto-tempo-parietal regions. These results suggest that the processing of semantic associations presented in different modalities lead to modality-specific activation caused by early access routes. However, common activation for both modalities refers to a common neural network for semantic processing suggesting amodal processing. Hum Brain Mapp, 2009. © 2009 Wiley-Liss, Inc.