Optimized neural coding? control mechanisms in large cortical networks implemented by connectivity changes

Authors

  • Katy A. Cross,

    Corresponding author
    1. Neuroscience Interdepartmental Program, University of California, Los Angeles
    2. Ahmanson-Lovelace Brain Mapping Center, University of California, Los Angeles
    • Ahmanson-Lovelace Brain Mapping Center, 660 Charles E. Young Dr. South, Los Angeles, CA 90095, USA
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  • Marco Iacoboni

    1. Ahmanson-Lovelace Brain Mapping Center, University of California, Los Angeles
    2. Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles
    3. Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles
    4. Brain Research Institute, University of California, Los Angeles
    5. David Geffen School of Medicine, University of California, Los Angeles
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Abstract

Using functional magnetic resonance imaging, we show that a distributed fronto-parietal visuomotor integration network is recruited to overcome automatic responses to both biological and nonbiological cues. Activity levels in these areas are similar for both cue types. The functional connectivity of this network, however, reveals differential coupling with thalamus and precuneus (biological cues) and extrastriate cortex (nonbiological cues). This suggests that a set of cortical areas equally activated in two tasks may accomplish task goals differently depending on their network interactions. This supports models of brain organization that emphasize efficient coding through changing patterns of integration between regions of specialized function. Hum Brain Mapp, 2013. © 2011 Wiley Periodicals, Inc.

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