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HBM_21440_sm_SuppFigures.pdf9986KFigure 1: Correlation Map of VPW Values with Amplitude of BOLD Signal Change During Visual Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged visual activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 2: Correlations of NAA Concentrations with VPW Values Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. The extent of NAA data is marked by the white boundary curve. Third row: Group-averaged VPW values. (a) Selected significantly inverse correlated region within white matter of the internal capsule. (b) Selected significantly inverse correlated region within prefrontal white matter and white matter. Figure 3: Correlations of NAA Concentrations with FA Values Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. The extent of NAA data is marked by the white boundary curve. Third row: Group-averaged FA values. (a) Selected significantly inverse correlated region within thalamus. (b) Selected significantly correlated region within superior longitudinal fasciculus of white matter. Figure 4: Correlations of NAA concentrations with Amplitude of BOLD Signal Change During Visual Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. The extent of NAA data is marked by the white boundary curve. Third row: Group-averaged visual activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 5: Correlations of NAA concentrations with Amplitude of BOLD Signal Change During Auditory Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. The extent of NAA data is marked by the white boundary curve. Third row: Group-averaged auditory activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 6: Correlations of NAA concentrations with Amplitude of BOLD Signal Change During Motor Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. The extent of NAA data is marked by the white boundary curve. Third row: Group-averaged motor activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. (a) Selected significantly correlated region within cuneate cortex. (b) Selected significantly inverse correlated region within primary motor cortex. Figure 7: Correlations of FA values with Amplitude of BOLD Signal Change During Auditory Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged auditory activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. (a) Selected significantly inverse correlated region within primary auditory cortex. (b) Selected significantly inverse correlated region within anterior cingulate cortex. Figure 8: Correlations of FA values with Amplitude of BOLD Signal Change During Motor Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged motor activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 9: Correlations of FA values with Amplitude of BOLD Signal Change During Visual Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged visual activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 10: Correlations of CPT Attention T-Score with Amplitude of BOLD Signal Change During Auditory Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged auditory activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. (a) Selected significantly inverse correlated region within primary auditory cortex. (b) Selected significantly inverse correlated region within posterior cingulate cortex. Figure 11: Correlations of CPT Attention T-Score with Amplitude of BOLD Signal Change During Visual Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged visual activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. (a) Selected significantly inverse correlated region within superior temporal lobe and cuneate cortex. (b) Selected significantly inverse correlated region within superior frontal cortex and posterior cingulate cortex. Figure 12: Correlations of CPT Attention T-Score with VPW Values Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged VPW values. Figure 13: Correlations of Full Scale IQ with Amplitude of BOLD Signal Change During Visual Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged visual activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. Figure 14: Correlations of Full Scale IQ with Amplitude of BOLD Signal Change During Motor Activation Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged motor activation BOLD signal amplitude map. The color bar used to encode activations is at the top right of the figure. (a) Selected significantly inverse correlated region within anterior cingulate cortex and middle occipital gyrus. (b) Selected significantly inverse correlated region within posterior cingulate cortex. Figure 15: Correlations of Full Scale IQ with VPW Values Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged VPW values. (a) Selected significantly correlated region within putamen and left anterior corona radiata. (b) Selected significantly correlated region within left superior corona radiata. Figure 16: Correlations of Full Scale IQ with FA Values Correlation coefficients with p-value < 0.5 are color encoded and displayed, and those with p-value < 0.05 are significant correlations. The color bar used to encode correlations is at the top right of the figure. First row: Group-averaged T1-weighted image. Second row: Color-coded correlation coefficients overlaid onto the average T1-weighted image. Third row: Group-averaged FA values. (a) Selected significantly correlated region within right anterior corona radiata and left superior longitudinal fasciculus. (b) Selected significantly correlated region within right cingulum.

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