The cortical control of cycling exercise in stroke patients: An fNIRS study

Authors

  • Pei-Yi Lin,

    1. Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan
    2. The Optics Division, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, MA, U.S.A.
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  • Jia-Jin Jason Chen,

    1. Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan
    2. Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan
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    • Pei-Yi Lin and Jia-Jin Jason Chen contributed equally to this work.

  • Sang-I Lin

    Corresponding author
    1. Department of Physical Therapy, National Cheng Kung University, Tainan, Taiwan
    2. Institute of Allied Health Sciences, National Cheng Kung University, Tainan, Taiwan
    • Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan
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Department of Physical Therapy, National Cheng Kung University, No. 1 University Rd, Tainan, Taiwan. E-mail: lin31@mail.ncku.edu.tw

Abstract

Stroke survivors suffering from deficits in motor control typically have limited functional abilities, which could result in poor quality of life. Cycling exercise is a common training paradigm for restoring locomotion rhythm in patients. The provision of speed feedback has been used to facilitate the learning of controlled cycling performance and the neuromuscular control of the affected leg. However, the central mechanism for motor relearning of active and passive pedaling motions in stroke patients has not been investigated as extensively. The aim of this study was to measure the cortical activation patterns during active cycling with and without speed feedback and during power-assisted (passive) cycling in stroke patients. A frequency-domain near-infrared spectroscopy (FD-NIRS) system was used to detect the hemodynamic changes resulting from neuronal activity during the pedaling exercise from the bilateral sensorimotor cortices (SMCs), supplementary motor areas (SMAs), and premotor cortices (PMCs). The variation in cycling speed and the level of symmetry of muscle activation of bilateral rectus femoris were used to evaluate cycling performance. The results showed that passive cycling had a similar cortical activation pattern to that observed during active cycling without feedback but with a smaller intensity of the SMC of the unaffected hemisphere. Enhanced PMC activation of the unaffected side with improved cycling performance was observed during active cycling with feedback, with respect to that observed without feedback. This suggests that the speed feedback enhanced the PMC activation and improved cycling performance in stroke patients. Hum Brain Mapp 34:2381–2390, 2013. © 2012 Wiley Periodicals, Inc.

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