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Structural abnormalities in the dyslexic brain: A meta-analysis of voxel-based morphometry studies

Authors

  • Fabio Richlan,

    Corresponding author
    1. Department of Psychology and Center for Neurocognitive Research, University of Salzburg, Salzburg, Austria
    • Department of Psychology and Center for Neurocognitive Research, University of Salzburg, Hellbrunnerstr. 34, 5020 Salzburg, Austria. E-mail: fabio.richlan@sbg.ac.at

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  • Martin Kronbichler,

    1. Department of Psychology and Center for Neurocognitive Research, University of Salzburg, Salzburg, Austria
    2. Neuroscience Institute and Department of Neurology, Christian Doppler Clinic, Paracelsus Private Medical University, Salzburg, Austria
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  • Heinz Wimmer

    1. Department of Psychology and Center for Neurocognitive Research, University of Salzburg, Salzburg, Austria
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Abstract

We used coordinate-based meta-analysis in order to objectively quantify gray matter abnormalities reported in nine Voxel-Based Morphometry studies of developmental dyslexia. Consistently across studies, reduced gray matter volume in dyslexic readers was found in the right superior temporal gyrus and left superior temporal sulcus. These results were related to findings from previous meta-analyses on functional brain abnormalities in dyslexic readers. Convergence of gray matter reduction and reading-related underactivation was found for the left superior temporal sulcus. Recent studies point to the presence of both functional and structural abnormalities in left temporal and occipito-temporal brain regions before reading onset. Hum Brain Mapp 34:3055–3065, 2013. © 2012 Wiley Periodicals, Inc.

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