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Abstract

A simple and convenient method for the preparation of Schiff bases is developed. In this method, the Schiff base compounds were prepared from the reaction of carbonyl compounds with primary amines. In this reaction, P2O5/SiO2 have catalyzed the Schiff base formation in dry media under solvent-free conditions. Advantages of this method are use of an inexpensive and efficient catalyst, high yields of products, short reaction times, and simpli-city of the reaction and workup. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:43–47, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20383