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Abstract

The treatment of indole with structurally diverse aldehydes in the presence of catalytic amount of inorganic-supported polyoxometalates, heterogeneous, reusable and efficient catalysts at room temperature gave the corresponding bis-indolylmethanes in excellent yields and shorter reaction times under solvent-free conditions. The catalyst can be reused for several times, but it will be less active. © 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:325–331, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20554