Dedicated to Professor Renji Okazaki on the occasion of his 77th birthday.
Synthesis of Multicyclic Heterocycles Initiated by C–H Bond Activation Along with “Rollover” Using a Rh(III) Catalyst
Version of Record online: 20 MAY 2014
© 2014 Wiley Periodicals, Inc.
Special Issue: Special Issue in Honor of Professor Renji Okazaki on the Occasion of his Kiju (77th Birthday)
Volume 25, Issue 5, pages 379–388, November 2014
How to Cite
Shibata, T. and Takayasu, S. (2014), Synthesis of Multicyclic Heterocycles Initiated by C–H Bond Activation Along with “Rollover” Using a Rh(III) Catalyst. Heteroatom Chem., 25: 379–388. doi: 10.1002/hc.21158
- Issue online: 29 OCT 2014
- Version of Record online: 20 MAY 2014
- Manuscript Revised: 27 MAR 2014
- Manuscript Received: 30 JAN 2014
- Grand-in-aid for Scientific Research on Innovative Area, “Molecular Activation Directed toward Straightforward Synthesis,” MEXT, JST, ACT-C
- Excellent Graduate School (Practical Chemical Wisdom), Waseda University, MEXT, Japan
Various multicyclic heterocycles were synthesized via “rollover” as the key pathway using a Rh(III) catalyst with a catalytic amount of sodium pivalate or copper(II) acetate. 3-Alkynyl-2-heteroarylpyridines were transformed into tri- or tetracyclic heterocycles containing two heteroatoms via an intramolecular alkyne insertion. 3-Aryloyl-2-arylpyridines were derived into 4-azafluoren-9-ols via the intramolecular carbonyl insertion.