Eating ability in head and neck cancer patients after treatment with chemoradiation: A 12-month follow-up study accounting for dropout
Article first published online: 23 JUN 2003
Copyright © 2003 Wiley Periodicals, Inc.
Head & Neck
Volume 25, Issue 12, pages 1034–1041, December 2003
How to Cite
Rademaker, A. W., Vonesh, E. F., Logemann, J. A., Pauloski, B. R., Liu, D., Lazarus, C. L., Newman, L. A., May, A. H., MacCracken, E., Gaziano, J. and Stachowiak, L. (2003), Eating ability in head and neck cancer patients after treatment with chemoradiation: A 12-month follow-up study accounting for dropout. Head Neck, 25: 1034–1041. doi: 10.1002/hed.10317
- Issue published online: 21 NOV 2003
- Article first published online: 23 JUN 2003
- Manuscript Accepted: 13 MAR 2003
- NIH P01 CA40007
- NIH P50 DE/CA11921
- generalized linear models;
- head and neck cancer
Head and neck cancer patients treated with chemoradiation have difficulty eating a normal diet. This study was designed to characterize eating ability over 12 months after chemoradiation treatment. Analyses take patient dropout into account.
Two hundred fifty-five patients with head and neck cancer treated with chemoradiation were followed for 12 months. Eating ability was analyzed using generalized linear model methods that accounted for non-ignorable dropout.
Eating ability was compromised immediately after treatment and improved over 12 months to near pretreatment levels. Ability to eat at most 50% of the diet orally did not return to baseline levels (p < .05). However, the percent of patients eating a normal diet did return to baseline levels. Accounting for dropout modified the results, but the pattern of significance was similar.
Treatment of head and neck cancer with chemoradiation has a significant effect on eating ability, which improves after 12 months after treatment. © 2003 Wiley Periodicals, Inc. Head Neck 25: 000–000, 2003