The American Society of Anesthesiologists' class as a comorbidity index in a cohort of head and neck cancer surgical patients
Article first published online: 5 OCT 2001
Copyright © 2001 John Wiley & Sons, Inc.
Head & Neck
Volume 23, Issue 11, pages 985–994, November 2001
How to Cite
Reid, B. C., Alberg, A. J., Klassen, A. C., Koch, W. M. and Samet, J. M. (2001), The American Society of Anesthesiologists' class as a comorbidity index in a cohort of head and neck cancer surgical patients. Head Neck, 23: 985–994. doi: 10.1002/hed.1143
- Issue published online: 5 OCT 2001
- Article first published online: 5 OCT 2001
- Manuscript Accepted: 31 MAY 2001
- head and neck neoplasms;
- age >65 years;
We assessed the American Society of Anesthesiologists' (ASA) class, as a measure of comorbidity in comparison to the commonly used Charlson index for prognostic ability in a HNCA population.
Proportional hazards methods were applied to head and neck cancer patients whose treatment included surgery by the Johns Hopkins Otolaryngology service (n = 388).
The Charlson index and ASA class were modestly correlated (Spearman 0.36, p < .001). Compared with patients with ASA class 1 or 2, those with ASA class 3 or 4 had a two-fold elevated mortality rate (Relative Hazard (RH) = 2.00, 95% CI, 1.38–2.89). This association was stronger than observed for a Charlson index score of 1 or more compared with 0 (RH = 1.59, 95% CI, 1.17–2.17). Both the Charlson index and ASA class adjusted RHs displayed dose-response patterns (p value for trend < .001).
Compared with the Charlson index, the ASA class had comparable if not greater prognostic ability for mortality in this elderly HNCA population. © 2001 John Wiley & Sons, Inc. Head Neck 23: 985–994, 2001.