Tracheal mucormycosis presented as an intraluminal soft tissue mass
Article first published online: 14 MAY 2004
Copyright © 2004 Wiley Periodicals, Inc.
Head & Neck
Volume 26, Issue 6, pages 541–543, June 2004
How to Cite
Wolf, O., Gil, Z., Leider-Trejo, L., Khafif, A., Biderman, P. and Fliss, D. M. (2004), Tracheal mucormycosis presented as an intraluminal soft tissue mass. Head Neck, 26: 541–543. doi: 10.1002/hed.20055
- Issue published online: 20 MAY 2004
- Article first published online: 14 MAY 2004
- Manuscript Accepted: 9 JAN 2004
- diabetic ketoacidosis;
- fungal infection;
Mucormycosis is a potentially lethal disease caused by an opportunistic fungal infection. It occurs mostly in diabetic or immunosuppressed patients and usually involves the lungs or paranasal sinuses.
We report a rare case of a patient with diabetic ketoacidosis who presented with progressive cough and dyspnea. CT of the neck and chest showed an intraluminal soft-tissue mass extending from the first tracheal ring to the thoracic inlet, causing severe destruction of the trachea. Direct laryngoscopy and biopsy demonstrated hyphal invasion with architecture typical of invasive mucormycosis.
The patient underwent resection of the upper trachea and prolonged amphotericin B therapy and is disease free at 24 months after surgery.
In patients with diabetes presenting with progressive hoarseness, dyspnea, and endobronchial mass, a fungal infection should be considered. In case of invasive tracheal mucormycosis, prompt diagnosis and early surgical resection may help improve survival. © 2004 Wiley Periodicals, Inc. Head Neck26: 541–543, 2004