Surgical margin is important to evaluate the adequacy of surgery related to tongue cancer. Despite the distances of margins, tumor components comprising the involved margins should also be investigated. Our aim was to explore the influences of tumor satellites on the clinical outcomes of involved margins.
Two hundred twenty-five patients with fresh tongue cancer were investigated. Nineteen patients with pathologically confirmed involved margins were enrolled. Based on the analysis of tumor components of involved margins, they were classified into 2 groups of either tumor-satellite involved margins (SMs) or main-tumor involved margins (MMs).
The results showed that the clinical stages distribution was different: advanced stages in the MM group, and earlier in SM (p = .028). SM group had a higher incidence of neck recurrence (p = .040). Nonetheless, no difference in the disease-specific survival was noted.
Tumor-satellite involved margins should be regarded as a worse prognosticator in tongue cancer. © 2008 Wiley Periodicals, Inc. Head Neck, 2008