Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma
Article first published online: 30 APR 2009
Copyright © 2009 Wiley Periodicals, Inc.
Head & Neck
Volume 31, Issue 6, pages 765–772, June 2009
How to Cite
Yuen, A. P.-W., Ho, C. M., Chow, T. L., Tang, L. C., Cheung, W. Y., Ng, R. W.-M., Wei, W. I., Kong, C. K., Book, K. S., Yuen, W. C., Lam, A. K.-Y., Yuen, N. W.-F., Trendell-Smith, N. J., Chan, Y. W., Wong, B. Y.-H., Li, G. K.-H., Ho, A. C.-W., Ho, W. K., Wong, S. Y. and Yao, T.-J. (2009), Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma. Head Neck, 31: 765–772. doi: 10.1002/hed.21033
- Issue published online: 6 MAY 2009
- Article first published online: 30 APR 2009
- Manuscript Accepted: 26 SEP 2008
There are controversies on the benefits of elective neck dissection (END) for oral tongue carcinoma.
This is a prospective randomized study of elective selective I, II, III neck dissection versus observation for N0 neck of stage I to II oral tongue carcinoma. There were 35 patients on the observation arm and 36 patients on the END arm. The main outcome assessment parameters are node-related mortality and disease-specific survival rate.
There were 11 patients in the observed arm and 2 patients in the END arm who developed nodal recurrence alone without associated local or distant recurrence. All 13 patients were salvaged, and no patient died of nodal recurrence. The 5-year disease-specific survival rate was 87% for the observation arm and was 89% for the END arm; the 2% difference was not significant.
Observation may be an acceptable alternative to END if strict adherence to a cancer surveillance protocol is followed. © 2009 Wiley Periodicals, Inc. Head Neck, 2009