Squamous cell carcinoma of the nasal vestibule 1993–2002: A nationwide retrospective study from DAHANCA
Article first published online: 27 MAY 2009
Copyright © 2009 Wiley Periodicals, Inc.
Head & Neck
Volume 31, Issue 12, pages 1593–1599, December 2009
How to Cite
Agger, A., von Buchwald, C., Madsen, A. R., Yde, J., Lesnikova, I., Christensen, C. B., Foghsgaard, S., Christensen, T. B., Hansen, H. S., Larsen, S., Bentzen, J., Andersen, E., Andersen, L. and Grau, C. (2009), Squamous cell carcinoma of the nasal vestibule 1993–2002: A nationwide retrospective study from DAHANCA. Head Neck, 31: 1593–1599. doi: 10.1002/hed.21132
- Issue published online: 9 NOV 2009
- Article first published online: 27 MAY 2009
- Manuscript Accepted: 18 FEB 2009
- nasal vestibule;
- squamous cell carcinoma;
- Wang, smoking;
A retrospective nationwide study of cancer of the nasal vestibule was conducted to evaluate classification systems and prognostic factors for treatment outcome.
Patients treated between 1993 and 2002 at head and neck oncology centers in Denmark were included.
The 5-year results were locoregional control 67%, overall survival 50%, cancer-specific survival 74%. Cancer-specific survival according to Wang classification was 83%, 63%, and 39% for T1, T2, T3, respectively (p < .000). Regarding T1 tumors, 5-year locoregional control for surgery, surgery + radiotherapy (RT), or RT was 94%, 87%, or 61%, respectively (p < .000). Fifty-four Gray in 18 fractions was found comparable with 66 Gy in 33 fractions regarding T1 tumors.
This national survey is the largest series of nasal vestibule cancer ever published. Wang classification is more prognostic and easier to use than the Union Internationale Contre le Cancer 2002. Surgery or hypofractionated RT can be used for T1 lesions, whereas larger lesions should be treated with combined approach. © 2009 Wiley Periodicals, Inc. Head Neck, 2009