Reliability and validity of the Vanderbilt Head and Neck Symptom Survey: A tool to assess symptom burden in patients treated with chemoradiation
Article first published online: 22 JUL 2009
Copyright © 2009 Wiley Periodicals, Inc.
Head & Neck
Volume 32, Issue 1, pages 26–37, January 2010
How to Cite
Murphy, B. A., Dietrich, M. S., Wells, N., Dwyer, K., Ridner, S. H., Silver, H. J., Gilbert, J., Chung, C. H., Cmelak, A., Burkey, B., Yarbrough, W. G., Sinard, R. and Netterville, J. (2010), Reliability and validity of the Vanderbilt Head and Neck Symptom Survey: A tool to assess symptom burden in patients treated with chemoradiation. Head Neck, 32: 26–37. doi: 10.1002/hed.21143
- Issue published online: 10 DEC 2009
- Article first published online: 22 JUL 2009
- Manuscript Accepted: 12 MAR 2009
We describe the development and validation of the Vanderbilt Head and Neck Symptom Survey (VHNSS), which was designed to screen for tumor- and treatment-specific symptoms in patients with head and neck cancer undergoing concurrent chemoradiation (CCR).
Using a 2-step card sort method, we identified high-impact and high-frequency toxicities in patients with head and neck cancer treated with CCR. This resulted in a 28-item questionnaire which scores symptoms on a 0 to 10 scale (none to severe). The tool was validated using data collected from 5 supportive care studies comprising a total sample of 332 patients with head and neck cancer.
Responses to the VHNSS items demonstrated a very consistent pattern (Cronbach's alpha = 0.943) with each item contributing substantially to the global index. Five symptom subscales were identified including “Nutrition,” “Pain,” “Voice,” “Swallow,” and “Mucous/Dry Mouth.” Each of the cluster scores demonstrated good internal consistency. The pattern of associations between the VHNSS and established tools indicated appropriate convergence and divergence. Comparison of global and subscale scores and objective measure were also in the expected direction providing further evidence of validity.
The findings provide support that the VHNSS is a valid and reliable tool to assess head and neck–specific symptom burden and function loss. Further research to evaluate this screening tool as a part of a systems approach to supportive care is warranted. © 2009 Wiley Periodicals, Inc. Head Neck, 2010