Article first published online: 18 AUG 2009
Copyright © 2009 Wiley Periodicals, Inc.
Head & Neck
Volume 32, Issue 4, pages 473–480, April 2010
How to Cite
Yildirim, G., Morrison, W. H., Rosenthal, D. I., Sturgis, E. M., Papadimitrakopoulou, V. A., Schwartz, D. L. and Garden, A. S. (2010), Outcomes of patients with tonsillar carcinoma treated with post-tonsillectomy radiation therapy. Head Neck, 32: 473–480. doi: 10.1002/hed.21207
The authors have no conflicts of interest with regards to the subject matter of this paper.
This work was presented at the 49th Annual Meeting of The American Society of Therapeutic Radiology and Oncology, Los Angeles, CA, 2007.
- Issue published online: 10 MAR 2010
- Article first published online: 18 AUG 2009
- Manuscript Accepted: 3 JUN 2009
- National Institutes of Health Research. Grant Number: CA-06294
- squamous cell carcinoma
Our aim was to evaluate the therapeutic outcomes of patients with squamous cell carcinoma of the tonsil that underwent tonsillectomies followed by radiotherapy.
A search of the database maintained within the Department of Radiation Oncology at The University of Texas M. D. Anderson Cancer Center identified 120 patients with carcinoma of the tonsil who were irradiated between 1979 and 2004 following total gross removal of their disease by tonsillectomy.
Thirty-six patients had stage III disease and 64 patients had stage IV disease. Only 12 patients received systemic chemotherapy. With median follow-up of 51 months, the 5-year local-regional control rate, recurrence-free survival rate, and overall survival rates were 97%, 92%, and 86%, respectively.
Patients who undergo tonsillectomies resulting in total gross removal of their primary disease followed by radiation have excellent outcomes. Our common practice is to deliver 66 Gy to the tonsillar bed. This practice has resulted in extremely high local control rates. © 2009 Wiley Periodicals, Inc. Head Neck, 2010