Combined therapy for thyroid squamous cell carcinoma




Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis.

Methods and Results.

We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy.


Our patient now has a recurrence-free survival of >20 months, longer than the mean survival described in the literature. © 2010 Wiley Periodicals, Inc. Head Neck, 2012