Effect of intraoral low-level laser therapy on quality of life of patients with head and neck cancer undergoing radiotherapy
Article first published online: 5 APR 2011
Copyright © 2011 Wiley Periodicals, Inc.
Head & Neck
Volume 34, Issue 3, pages 398–404, March 2012
How to Cite
Oton-Leite, A. F., Corrêa de Castro, A. C., Morais, M. O., Pinezi, J. C. D., Leles, C. R. and Mendonça, E. F. (2012), Effect of intraoral low-level laser therapy on quality of life of patients with head and neck cancer undergoing radiotherapy. Head Neck, 34: 398–404. doi: 10.1002/hed.21737
- Issue published online: 7 FEB 2012
- Article first published online: 5 APR 2011
- Manuscript Accepted: 4 JAN 2011
- Manuscript Revised: 10 DEC 2010
- Manuscript Received: 28 SEP 2010
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Grant Number: 402322/2008 8
- head and neck cancer;
- laser therapy;
- quality of life;
Low-level laser therapy has been used to reduce complications of head and neck cancer treatment. The aim was to assess the impact of laser in the quality of life (QOL) of patients receiving radiotherapy.
Sixty outpatients were randomly assigned into 2 groups. The laser group received applications and the placebo group received sham laser. QOL was assessed using the University of Washington QOL questionnaire. A repeated-measures analysis of variance (ANOVA) was used for comparisons of overall QOL scores and Mann–Whitney test compared changes in domain scores.
A decrease in QOL scores was observed in both groups and the reduction in the laser group was significantly lower (p < .01). Changes in QOL scores regarding pain, chewing, and saliva domains were evident in the placebo group. Both health-related QOL and overall QOL were rated higher by patients who received laser therapy.
Laser therapy reduces the impact of radiotherapy on the QOL of patients with head and neck cancer. © 2011 Wiley Periodicals, Inc. Head Neck, 2012