This work was presented at the 2010 American Head and Neck Society Research Workshop in Washington, DC, October 30, 2010.
Venous thromboembolism in patients with head and neck cancer after surgery†
Article first published online: 2 FEB 2012
Copyright © 2012 Wiley Periodicals, Inc.
Head & Neck
Volume 35, Issue 1, pages 4–9, January 2013
How to Cite
Thai, L., McCarn, K., Stott, W., Watts, T., Wax, M. K., Andersen, P. E. and Gross, N. D. (2013), Venous thromboembolism in patients with head and neck cancer after surgery. Head Neck, 35: 4–9. doi: 10.1002/hed.22920
- Issue published online: 15 DEC 2012
- Article first published online: 2 FEB 2012
- Manuscript Accepted: 3 NOV 2011
- Manuscript Revised: 1 SEP 2011
- Manuscript Received: 23 DEC 2010
- venous thromboembolism;
- deep venous thrombosis;
- pulmonary embolism;
- squamous cell carcinoma;
The purpose of this study was to report the incidence of venous thromboembolism (VTE) in patients with head and neck cancer after surgery.
This was a single-institution, retrospective cohort: 134 patients underwent resection and simultaneous microvascular reconstruction. The primary endpoint was identification of confirmed or suspicious VTE within 30 days of surgery.
Two subjects (1.4%) with confirmed VTE (1 pulmonary embolism, 1 deep venous thrombosis) and 6 subjects (4.4%) with suspicious VTE (1 acute respiratory failure, 1 sudden cardiac arrest, and 4 cases of leg edema without imaging) were identified. The strongest predictors of possible VTE were prior VTE (p = .004; odds ratio [OR], 25.11; 95% confidence interval [CI], 1.13–556.40), red cell transfusion (p = .009; OR, 1.80; 95% CI, 1.16–2.80), high body mass index (p = .015, OR, 1.29, 95% CI, 1.05–1.58), and older age (p = .046; OR, 1.10; 95% CI, 1.00–1.19).
The incidence of VTE in patients with head and neck cancer after resection and microvascular reconstruction ranged from 1.4% to 5.8%. © 2012 Wiley Periodicals, Inc. Head Neck, 2013