Maté consumption and risk of oral cancer: Case-control study in Uruguay
Article first published online: 8 AUG 2012
Copyright © 2012 Wiley Periodicals, Inc.
Head & Neck
Volume 35, Issue 8, pages 1091–1095, August 2013
How to Cite
Deneo–Pellegrini, H., De Stefani, E., Boffetta, P., Ronco, A. L., Acosta, G., Correa, P. and Mendilaharsu, M. (2013), Maté consumption and risk of oral cancer: Case-control study in Uruguay. Head Neck, 35: 1091–1095. doi: 10.1002/hed.23080
- Issue published online: 22 JUL 2013
- Article first published online: 8 AUG 2012
- Manuscript Accepted: 4 MAY 2012
- oral cancer;
- maté consumption;
In the period 1990 to 2001, a case-control study on oral cancer and maté consumption was conducted at the Cancer Institute of Uruguay.
The study included 696 newly diagnosed cases with squamous cell carcinoma and 696 controls afflicted with nonneoplastic conditions not related to tobacco smoking and alcohol drinking. The participants were matched on age and residence and the study was restricted to men.
In order to control confounding for tobacco and alcohol, we fitted 2 models. According to model 1, the odds ratio (OR) for maté consumption was 1.15 (95% confidence interval [CI], 0.76–1.73), whereas the results for model 2 showed an OR of 3.47 (95% CI, 1.60–7.52).
The inclusion of a term for the interaction between maté and smoking (or drinking) was rewarding and the ORs were even higher than those observed with the crude estimates. Head Neck, 2013