Pilot, randomized trial of resistance exercise during radiation therapy for head and neck cancer
Article first published online: 30 JUL 2012
Copyright © 2012 Wiley Periodicals, Inc.
Head & Neck
Volume 35, Issue 8, pages 1178–1188, August 2013
How to Cite
Rogers, L. Q., Anton, P. M., Fogleman, A., Hopkins–Price, P., Verhulst, S., Rao, K., Malone, J., Robbs, R., Courneya, K. S., Nanavati, P., Mansfield, S. and Robbins, K. T. (2013), Pilot, randomized trial of resistance exercise during radiation therapy for head and neck cancer. Head Neck, 35: 1178–1188. doi: 10.1002/hed.23118
- Issue published online: 22 JUL 2013
- Article first published online: 30 JUL 2012
- Manuscript Accepted: 28 MAY 2012
- Excellence in Academic Medicine grant of the Southern Illinois University School of Medicine
- body composition;
- quality of life
The purpose of this study was to determine the feasibility of a randomized trial of resistance exercise in patients with head and neck cancer receiving radiation.
Fifteen patients with head and neck cancer receiving radiation were randomized to resistance exercise (using resistance bands) or control group. Resistance exercise occurred at the radiation therapy site (weeks 1–6) and home (weeks 7–12).
No serious adverse events occurred related to resistance exercise. Medium to large effect size differences favoring resistance exercise versus control group were noted for perceived fatigue at 6 weeks (smaller increase in fatigue for resistance exercise group; 7.4 vs 15.4, effect size [d] = −0.64), quality of life at 6 weeks (−7.0 vs −14.4, d = 0.52), and chair rise time (seconds) at 6 and 12 weeks (−1.6 vs 0.4, d = −.63 and −1.9 vs 0.1, d = −0.60, respectively).
Resistance exercise is safe and feasible in patients with head and neck cancer receiving radiation; a definitive trial is warranted. © 2012 Wiley Periodicals, Inc. Head Neck, 2013